Manchester United have the chance to put themselves in a promising position ahead of the Champions League group stage run-in.
With two wins and one defeat from three games, United head into the return legs top of their group and could, with results going their way, seal qualification to the knockout phase as soon as next week.
The encounter in Istanbul between the two sides saw the Turkish side pull of an unexpected upset, as United barely showed up.
The Reds’ have won their two league games since the defeat and will be hoping to put the visitors to the sword.
Marcus Rashford, who was visibly struggling against West Bromwich Albion, is expected to sit the game out whilst it is unlikely that Victor Lindelöf will be risked.
Edinson Cavani could make his first start for United and Donny van de Beek is likely to start for the third straight Champions League game.
Solskjær has confirmed that Dean Henderson will start once again, as he did in Istanbul.
Manchester United (4-2-3-1): Henderson; Wan-Bissaka, Tuanzebe, Maguire, Telles; McTominay, Fred; Van de Beek, Fernandes, Martial; Cavani